Pylorus Resection or Pylorus Preservation in partial Pancreatico-Duodenectomy: A randomized controlled trial (PROPP study).

Conditions

C25.0 D13.6

Klotz R, Diener MK, Schmidt T, Hackert T, Graf S, Fuchs HF, Grimminger P, Egberts JH, Gockel I, van der Sluis PC, Doerr-Harim C, Klose C, Feißt M, Mihaljevic AL.

2023-03-101 citations

10.1186/s13063-023-07134-1

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Busquets J, Martín S, Secanella L, Sorribas M, Cornellà N, Altet J, Peláez N, Bajen M, Carnaval T, Videla S, Fabregat J.

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10.1007/s00423-022-02583-9

Protocol of a prospective study investigating the association of PAncreatic parenchymal RISk factors with postoperative pancreatic fistula after partial pancreaticoduodenectomy (PARIS trial)

Fabian Schuh, Matthias A. Fink, Manuel Feißt, Christoph Eckert, Colette Dörr-Harim et al. (10 authors)

BMJ Open2022-04-012 citations

10.1136/bmjopen-2021-054138

Intraoperative endoluminal pyloromyotomy for reduction of delayed gastric emptying after pylorus preserving partial pancreaticoduodenectomy (PORRIDGE trial): study protocol for a randomised controlled trial.

Schrempf MC, Pinto DRM, Wolf S, Geissler B, Sommer F, Hoffmann M, Vlasenko D, Gutschon J, Anthuber M.

2022-01-252 citations

10.1186/s13063-022-06032-2

Pylorus resection versus pylorus preservation in pancreatoduodenectomy (PyloResPres): study protocol and statistical analysis plan for a German multicentre, single-blind, surgical, registry-based randomised controlled trial

Bernhard W. Renz, Christine Adrion, Carsten Klinger, Matthias Ilmer, Jan DʼHaese et al. (8 authors)

BMJ Open2021-11-019 citations

10.1136/bmjopen-2021-056191

Pylorus Resection Does Not Reduce Delayed Gastric Emptying After Partial Pancreatoduodenectomy

Thilo Hackert, Pascal Probst, Phillip Knebel, Colette Doerr-Harim, Thomas Brückner et al. (13 authors)

Annals of Surgery2017-09-0793 citations

10.1097/sla.0000000000002480

Pylorus resection or pylorus preservation in partial pancreatico-duodenectomy (PROPP study): study protocol for a randomized controlled trial.

Hackert T, Bruckner T, Dörr-Harim C, Diener MK, Knebel P, Hartwig W, Strobel O, Fritz S, Schneider L, Werner J, Büchler MW.

2013-02-1416 citations

10.1186/1745-6215-14-44

Interventions

Group 1: pylorus-preserving partial pancreatico-duodenectomy Group 2: partial pancreatico-duodenectomy with resection of the pylorus

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: elective partial pancreatico-duodenectomy, 18 years or older, written informed consent

Exclusion criteria

Exclusion criteria: impaired possibility for consent (mental or language), other studies interfering with the PROPP trial, no written informed consent

Design outcomes

Primary

Measure	Time frame
delayed gastric emptying (DGE) after partial pancreatico-duodenectomy within 30 days, evaluation on d 7, 14 and 30 according to the ISGPS (International Study Group of Pancreatic Surgery) definition (see references)	—

Secondary

Measure	Time frame
operation time, blood loss, morbidity according to the Clavien-Dindo classification, 30-day mortality, hospital stay, quality of life 30 days postoperative (EORTC QLQ PAN 26)	—

Countries

Germany

Contacts

Public ContactThilo Hackert

Universitätsklinikum Heidelberg

thilo_hackert@med.uni-heidelberg.de06221 5636258

Outcome results

None listed