Influence of a rehabilitative exercise program on physical, psychological and psychosocial parameters in prostate cancer patients

Influence of a rehabilitative exercise program on physical, psychological and psychosocial parameters in prostate cancer patients - ProRehab Study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00004184

Enrollment

200

Registered

2012-07-03

Start date

2008-02-13

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C61 C61

Interventions

Group 1: 15 month exercise program within a rehabilitative sports group Group 2: no intervention

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Patients with a prostate cancer disease who completed primary treatment; patients who underwent a radical prostatectomy or combination therapy (radical prostectomy + radiation); Patients who completed their primary treatment no longer than 6 to 12 weeks before the intervention begins; written consent

Exclusion criteria

Exclusion criteria: severe cardiac disease (NYHA III-IV); severe mental illness or chronic disease that rules out regular physical activities; (neo-)adjuvant chemotherapy; hormone therapy; irradiation without radical prostatectomy; regular physical activities of more than 60 minutes per week; current alcohol, drug, or medication abuse; insufficient german language skills

Design outcomes

Primary

Measure	Time frame
The primary endpoint is physical fitness, assessed with a spiroergometry on a treadmill at baseline, after 6 months and after in the intervention	—

Secondary

Measure	Time frame
Secondary endpoints are urinary incontinence measured with the 20-Min. Pad-Test at three assessment time points; erectile dysfunction assessed with the IIEF questionnaire at five assessment time points; testosterone, PSA, endostatin, VEGF and IL-6 assessed by taking blood samples at three measurements; general quality of life and prostate cancer-specific quality of life assessed with the EORTC-QLQ-C30 and EORTC-QLQ-PR25 questionnaire at five assessment time points; physical activity levels (MET score) assessed with the Freiburger questionnaire of Physical Activity at five assessment time points; adherence evaluated by an adherence questionnaire at five assessment time points.	—

Measure

Time frame

Secondary endpoints are urinary incontinence measured with the 20-Min. Pad-Test at three assessment time points; erectile dysfunction assessed with the IIEF questionnaire at five assessment time points; testosterone, PSA, endostatin, VEGF and IL-6 assessed by taking blood samples at three measurements; general quality of life and prostate cancer-specific quality of life assessed with the EORTC-QLQ-C30 and EORTC-QLQ-PR25 questionnaire at five assessment time points; physical activity levels (MET score) assessed with the Freiburger questionnaire of Physical Activity at five assessment time points; adherence evaluated by an adherence questionnaire at five assessment time points.

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Countries

Germany

Contacts

Public ContactFreerk Baumann

Deutsche Sporthochschule Köln Institut für Kreislaufforschung und Sportmedizin Abt. Molekulare und Zelluläre Sportmedizin

f.baumann@dshs-koeln.de0221/49824821

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 25, 2026