Multimodal therapy concept and aerobic training in breast cancer patients with chronic cancer-related fatigue syndrome (CRF): a comprehensive cohort design study

Multimodal therapy concept and aerobic training in breast cancer patients with chronic cancer-related fatigue syndrome (CRF): a comprehensive cohort design study - CRF-study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00003736

Enrollment

114

Registered

2012-06-19

Start date

2011-06-22

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer patients with fatigue-syndrom G93.3

Interventions

Group 1: aerobic training, minimum 30 minutes, once a week, 10 interventions Group 2: multimodal therapy, minimum 30 minutes, once a week, 10 interventions Group 3: multimodal therapy + aerobic traini

Eligibility

Sex/Gender

Female

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Not any chemotherapy, radiotherapy, surgery in the last 6 month. Final diagnosis from June 2009.

Exclusion criteria

Exclusion criteria: untreated cardiac, thyroid, nephric desease or untreated circulatory disorder

Design outcomes

Primary

Measure	Time frame
Cancer Fatigue Scale (CFS-D), german version: data collection: first intervention, last intervention, 6 months after last intervention Pittsburgh Sleep Quality Index (PSQI): data collection: first intervention, last intervention, 6 months after last intervention	—

Secondary

Measure	Time frame
Quality of life index with EORTC QLQ-C30, time of measurement: first intervention, last intervention, 6 months after last intervention. General vegetative status with Trait aR, time of measurement: first intervention, last intervention, 6 months after last intervention. Actual vegetative status with State aR, time of measurement: first intervention, last intervention, 6 months after last intervention. Anxiety and Depression with Hospital Anxiety and Depression Scale (HADS), time of measurement: first intervention, last intervention, 6 months after last intervention. Self-regulation with Scale of self-regulation, time of measurement: first intervention, last intervention, 6 months after last intervention. Internal coherence with ICS, time of measurement: first intervention, last intervention, 6 months after last intervention. Mental participation of eurythmics with Bewegung und innere Kongruenz (ICPH, Version 2.1), time of measurement: last intervention and 6 months after last intervention. Mental participation of drawing therapy with Innere Kongruenz und Einklang mit der Therapie (ICPTh, Version 1.0), time of measurement: last intervention and 6 months after last intervention. Physiologic measurements: rhythm of rest and activity with 72-hours-Aktimeter and 24-hours-ECG, time of measurement: 0-3 weeks before first intervention, 0-3 weeks after last intervention. Scales for therapists: erythmics: HFET-2, time of measurement: 0-3 weeks before first intervention, 0-3 weeks after last intervention. drawing therapy: AKT-DIAG, time of measurement: first intervention, 0-3 weeks after last intervention.	—

Measure

Time frame

Quality of life index with EORTC QLQ-C30, time of measurement: first intervention, last intervention, 6 months after last intervention. General vegetative status with Trait aR, time of measurement: first intervention, last intervention, 6 months after last intervention. Actual vegetative status with State aR, time of measurement: first intervention, last intervention, 6 months after last intervention. Anxiety and Depression with Hospital Anxiety and Depression Scale (HADS), time of measurement: first intervention, last intervention, 6 months after last intervention. Self-regulation with Scale of self-regulation, time of measurement: first intervention, last intervention, 6 months after last intervention. Internal coherence with ICS, time of measurement: first intervention, last intervention, 6 months after last intervention. Mental participation of eurythmics with Bewegung und innere Kongruenz (ICPH, Version 2.1), time of measurement: last intervention and 6 months after last intervention. Mental participation of drawing therapy with Innere Kongruenz und Einklang mit der Therapie (ICPTh, Version 1.0), time of measurement: last intervention and 6 months after last intervention. Physiologic measurements: rhythm of rest and activity with 72-hours-Aktimeter and 24-hours-ECG, time of measurement: 0-3 weeks before first intervention, 0-3 weeks after last intervention. Scales for therapists: erythmics: HFET-2, time of measurement: 0-3 weeks before first intervention, 0-3 weeks after last intervention. drawing therapy: AKT-DIAG, time of measurement: first intervention, 0-3 weeks after last intervention.

—

Countries

Germany

Contacts

Public ContactDanilo Pranga

Forschungsinstitut Havelhöhe (FIH)

dpranga@havelhoehe.de030 36501338

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 10, 2026