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Liver pre-conditioning by the portal vein embolization (PVE) before liver resection.

Liver pre-conditioning by the portal vein embolization (PVE) before liver resection. - Volume

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00003723
Enrollment
70
Registered
2012-05-16
Start date
2012-04-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C22

Interventions

Group 1: Patients who become PVE prior to liver resection will be included. Before and after PVE as well as one, two, three and four weeks after PVE and after resection at days 1, 10 and 85 the liver

Sponsors

Klinik für Allgemein-, Viszerall- und Transplantationsmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patient is a male or female, obtaining a PVE during preoperative conditioning process 2. Patient is over 18 years of age 3. Patient provides written informed consent

Exclusion criteria

Exclusion criteria: 1. Patient with a GFR < 30 ml/min/1,73 m2 2. Patient has or requires an implantable electronic defibrillator, pacemaker or other ferromagnetic implants 3. Patient with congenital long-QT-syndrom or corresponding family history 4. Patient has a known allergy to the contrast agent Primovist ® 5. Patient is treated with drugs prolonging the repolarization, e.g. Class III - anti arrhythmic agents (e.g. Amiodaron, Sotalol). 6. Patient has already underwent liver surgery (cholecystectomia is not a reason for exclusion 7. Any factors, decreasing the ability to apply and cooperate during the (e.g. mental dysfunction, claustrophobia or abuse of drugs) 8. Patient is pregnant or lactating

Design outcomes

Primary

MeasureTime frame
Volume function analysis at the time points: before and after PVE as well as one, two, three and four weeks after PVE and after resection at days 1, 10 and 85.

Countries

Germany

Contacts

Public ContactMaciej Malinowski

Klinik für Allgemein-, Viszerall- und Transplantationschirurgie

maciej.malinowski@charite.de+49 30 450 552 001

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026