Healthy participants
Conditions
Interventions
Group 1: 10 healthy adult male subjects (20 to 40-years old) will be instructed to eat 0.3 g/d/kg commercially available flaxseeds (Brauch GmbH & Co KG) over a period of 7 days in addition to their us
Sponsors
Technische Universität München
Zentral Institut für Ernährungs- und Lebensmittelforschung
Abteilung Biofunktionalität
Nachwuchsgruppe Intestinales Mikrobiom
Eligibility
Sex/Gender
Male
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Young adult healthy male subject (20 to 40 years old)
Exclusion criteria
Exclusion criteria: 1) known allergy to flaxseeds; 2) Under- or overweight (BMI 27); 3) chronic diseases (inflammatory bowel diseases, type-1 and type-2 diabetes, dermatitis, food allergies); 4) medication within the last two months before the start of the study (antibiotics, anti-inflammatory drugs); 5) use of pre- or probiotics within the last two months before the start of the study; 6) participation to another clinical trial within the last two months before the start of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Fecal bacterial diversity and composition analysis (pyrosequencing and in situ hybridization); 2) Lignan concentrations in feces, blood and urine (high-pressure liquid chromatography). Time points of measurement: d0, 1, 7 (before intervention), 14 (after intervention), 21 | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolite profiling in feces, blood and urine (mass spectrometry). Time points of measurement: d0, 1, 7 (before intervention), 14 (after intervention), 21 | — |
Countries
Germany
Contacts
Public ContactThomas Clavel
Technische Universität München Zentral Institut für Ernährungs- und Lebensmittelforschung Abteilung Biofunktionalität Nachwuchsgruppe Intestinales Mikrobiom
Outcome results
None listed