Obstructive lung diseases, asthma, COPD, cystic fibrosis J45 J44.9 E84
Conditions
Interventions
Group 1: Healthy adults
Tests to be performed:
Inclusion:
routine lung function test (spirometry and body plethysmography)
3 Nitrogen-Multiple Breath Washout Tests
3 Nitrogen-Single Breath Washout Te
Sponsors
Klinik Schillerhöhe, Robert-Bosch-Krankenhaus-GmbH,
Akademisches Lehrkrankenhaus der Universität Tübingen
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Healthy adults: Healthy nonsmoking adults 18-70 years without prior lung diaseases. Asthma patients: Clinical diagnosis of Asthma. Treatment step 2-4 (GINA). No history of smoking. ACT > 20 pts. COPD patients: Clinical diagnosis of COPD. GOLD I-III. Smoking history > 10 PY. Cystic fibrosis patients: Clinical diagnosis of CF. No history of smoking. FEV1 > 40 % pred.
Exclusion criteria
Exclusion criteria: Age < 18 years, Incapable of giving consent to the study, Pregnancy, Severe cardiac comorbidity, Known intolerance to salbutamol Respiratory infection or change of medication within the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Variability and reproducability of Nitrogen-Single Breath Washout Test (N2-SBW), Nitrogen-Multiple Breath Washout Test (N2-MBW) and Double Tracer Gas Singl Breath Washout Test (DTG-SBW parameters). Differences in N2-SBW, N2-MBW and DTG-SBW parameters between patient populations | — |
Secondary
| Measure | Time frame |
|---|---|
| Define new Double Tracer Gas Single Breath Washout Test parameters | — |
Countries
Germany
Contacts
Public ContactKim Husemann
Klinik Schillerhöhe, Robert-Bosch-Krankenhaus-GmbH Akademisches Lehrkrankenahus der Universität Tübingen
Outcome results
None listed