DSM-IV: 295.30 (schizophrenia, paranoid type) F20
Conditions
Interventions
Group 1: patients with schizophrenia
investigations: polysomnography, neuropsychological assessments, sleep-dependent memory consolidation, assessment of sleep-wake rhythm, fMRI
Group 2: healthy control subjects
investigations: polysomnography, neuropsychological assessments, sleep-dependent memory consolidation, assessment of sleep-wake rhythm, fMRI
Sponsors
Zentralinstitut für Seelische Gesundheit, Medizinische Fakultät Mannheim / Universität heidelberg, Klinik für Psychiatrie und Psychotherapie
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: diagnosis of schizophrenia or healthy control subject, good german language knowledge, ability to agree to the study procedures
Exclusion criteria
Exclusion criteria: acute exacerbation, psychiatric comorbidity, psychopharmacological treatment except of monotherapy with atypical antipsychotic (schizophrenia patients), severe neurological or medical disorder, metal implants, large tattoos
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| polysomnographic sleep parameters and sleep micro-architecture (group comparison, polysomnographic assessment at one point of time) and their correlation with measures of sleep-dependent memory consolidation (polysomnography paralleled by memory consolidation paradigms) | — |
Secondary
| Measure | Time frame |
|---|---|
| cognitive functions (neuropsychological assessment), sleep-wake-rhythm (actimetry), neuronal correlates (fMRI), investigated at one point of time | — |
Countries
Germany
Contacts
Public ContactClaudia Schilling
Zentralinstitut für Seelische Gesundheit, Medizinische Fakultät Mannheim / Universität heidelberg, Klinik für Psychiatrie und Psychotherapie
Outcome results
None listed