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Prevalence of colorectal cancer in symptomatic and asymptomatic patients undergoing total coloscopy A prospective, multi-center, case-control endoscopy study in a federal state in Germany

Prevalence of colorectal cancer in symptomatic and asymptomatic patients undergoing total coloscopy A prospective, multi-center, case-control endoscopy study in a federal state in Germany

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00003503
Enrollment
1075
Registered
2013-09-03
Start date
2009-10-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C18

Interventions

Group 1: Symptomatic patients undergoing colonoscopy were investigated with respect to colon cancer and its precursor lesions Group 2: Asymptomatic screening participants were matched with patients fr

Sponsors

Universitätsklinik Frankfurt am Main
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to No maximum

Inclusion criteria

Inclusion criteria: patients undergoing colonoscopy under outpatient conditions. Only patients undergoing first colonoscopy in life were evaluated. Symptoms included tumour-suspicious symptoms (altered bowel habits, weight loss, anaemia, anorectal bleeding, positive fecal occult blood tests (FOBT), abdominal pain, constipation or diarrhoea). Eligible patients provided written informed consent. Complete colonoscopy is mandatory.

Exclusion criteria

Exclusion criteria: Persons with increased risk for CRC (surveillance after resection of a CRC, surveillance after polypectomy, known inflammatory bowel disease, FAP, HNPCC) and persons with the history of colorectal surgery were excluded in both study groups. The completeness of colonoscopy was a prerequisite for inclusion in both studies as well as for reimbursement by the health insurance

Design outcomes

Primary

MeasureTime frame
Prevalence of colorectal cancer and its precursor lesions in patients undergoing total colonoscopy in comparison to screening participants.

Countries

Germany

Contacts

Public ContactIrina Blumenstein

Universitätsklinikum Frankfurt am Main

blumenstein@em.uni-frankfurt.de++49 69 6301 5441

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026