Whole body vibration and balance training plus protein-rich nutrition to preserve postural control and muscle size during allogeneic haematopoietic cell transplantation

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00003492

Enrollment

200

Registered

2012-12-03

Start date

2017-06-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

all patients during allogeneic transplantation C92 C93 D46

Interventions

Group 1: patients in the verum group are receiving a sportstraining for 12 weeks mit 5 units/ week. It is consisting of: complete Whole body vibration and balance training and a endurance training add

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - All patients eligible for alloHCT - Age: 18-80 years - Signed informed consent

Exclusion criteria

Exclusion criteria: - Instable bone metastases

Design outcomes

Primary

Measure	Time frame
Sway path of centre of pressure (postural control) measure instrument: Kraftmessplatte (Kistler™ Kraftmessplatte, Kistler Instrumente GmbH Ostfildern, Deutschland) patients will be tested at the day of hospital admission T0 day + 30 after allogeneic transplantation T1 day + 100 after alloTX T2	—

Secondary

Measure	Time frame
- Gait speed (postural control) 10m gait control system (OPTOGAIT™, Microgate, VELAMED GmbH, Köln, Deutschland) - Stride-to-stride variability (postural control) 10m gait control system (OPTOGAIT™, Microgate, VELAMED GmbH, Köln, Deutschland) - Muscle size of the quadriceps femoris muscle, ultrasound (Siemens Sonoline G40, 10.5 MHz, Germany). - Endurance capacity - Maximum voluntary contraction (MVC) of upper leg explovie power in Nm and Nm/s Isokinetic endurance measurement (CON-TREX MJ, CMV-AG, Schweiz) - Body composition (phase angle, fat-free mass, body cell mass) Bio electrical Impedanzanalysis (BIA (Nutrigard MS™, Data Input GmbH, Darmstadt, Germany) Body changes will be measured by BMI, BIA and Body composition - Polyneuropathy (tuning fork) - Fatigue, MFI - Quality of life, EORTC QLQ-C30 - Polyneuropathy, FACT&GOG-Ntx - Lifestyle; self developed questioneer - Transplant-specific outcome parameters "allo-all" Data-bank all seconday endpoints will be measured at day +100 and 1 year after the transplantation	—

Measure

Time frame

- Gait speed (postural control) 10m gait control system (OPTOGAIT™, Microgate, VELAMED GmbH, Köln, Deutschland) - Stride-to-stride variability (postural control) 10m gait control system (OPTOGAIT™, Microgate, VELAMED GmbH, Köln, Deutschland) - Muscle size of the quadriceps femoris muscle, ultrasound (Siemens Sonoline G40, 10.5 MHz, Germany). - Endurance capacity - Maximum voluntary contraction (MVC) of upper leg explovie power in Nm and Nm/s Isokinetic endurance measurement (CON-TREX MJ, CMV-AG, Schweiz) - Body composition (phase angle, fat-free mass, body cell mass) Bio electrical Impedanzanalysis (BIA (Nutrigard MS™, Data Input GmbH, Darmstadt, Germany) Body changes will be measured by BMI, BIA and Body composition - Polyneuropathy (tuning fork) - Fatigue, MFI - Quality of life, EORTC QLQ-C30 - Polyneuropathy, FACT&GOG-Ntx - Lifestyle; self developed questioneer - Transplant-specific outcome parameters "allo-all" Data-bank all seconday endpoints will be measured at day +100 and 1 year after the transplantation

—

Countries

Germany

Contacts

Public ContactSarah Kneis

Medizinische Universitätsklinik Freiburg Abtl. Häm/Onk

sarah.kneis@uniklinik-freiburg.de0049 0 761 270 73240

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026