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Detecting local recurrent prostate cancer: MRI:patterns of post-prostatectomy recurrence and of its response to salvege radiotherapy using Enhanced and Dynamic Contrast Enhanced (DCE) MRI

Detecting local recurrent prostate cancer: MRI:patterns of post-prostatectomy recurrence and of its response to salvege radiotherapy using Enhanced and Dynamic Contrast Enhanced (DCE) MRI

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00003469
Enrollment
33
Registered
2012-11-21
Start date
2011-03-24
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C61

Interventions

Group 1: Evaluation of patient data regarding the median PSA, the T stage, Gleason score before radical prostatectomy and after surgical resection. Evaluation of the patient data on the median age at

Sponsors

Universitätsklinikum Freiburg, Klinik für Strahlenheilkunde
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients with a history of prostate carcinoma Prostatavesikolektomie because of a biochemical (PSA) recurrence (definition of PSA recurrence: three consecutive rising PSA values ??above the nadir,> 3 months after surgery) - Have received no anti-hormonal therapy prior to radiotherapy - MRI scan prior to initiation of radiotherapy - PSA follow-up of at least 1 year after the end of radiotherapy

Exclusion criteria

Exclusion criteria: Clinical and imaging suspicion of lymph node metastases or distant metastases before initiation of radiation therapy to the pelvis

Design outcomes

Primary

MeasureTime frame
Sensitivity, specificity and accuracy of DCE-MRI without endorectal coil in the detection of local recurrent PC at very low PSA levels.

Secondary

MeasureTime frame
Correlation of tumor size to pre-RT PSA-level.

Countries

Germany

Contacts

Public ContactHans Christian Rischke

Universitätsklinikum Freiburg, Klinik für Strahlenheilkunde

hans.christian.rischke@uniklinik-freiburg.de0761/270-94760

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026