J96.99
Conditions
Interventions
Group 1: Body position: flat in bed, spontaneous breathing trial
Group 2: Body position: 30° elevated torso, spontaneous breathing trial
Group 3: Body position: sitting in bed, spontaneous breathing t
Sponsors
Uniklinik Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients during prolonged weaning will be recruited at the time point when at least 30min of spontaneous breathing can be performed without cardiorespiratory deteriorations. Patients should be tracheotomized with canula size ID 7,5 / 8.
Exclusion criteria
Exclusion criteria: Exclusion criteria are neuromuscular diseases, acute infections, minimal cooperation, implanted electrical devices or orthopedic limitations for certain body positions as requested by the study design.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint is the muscular activation in contrast to maximal voluntary activation in the distinct muscular groups in three different body positions (%max) (flat, 30° elevated torso, sitting in bed) as assessed by surface EMG of the respiratory muscles (parasternal, diaphragm, M. rectus abdominis) | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are differences in muscular activation with respect to maximal voluntary activation as assessed by surface EMG of the respiratory muscles between sitting with blocked tracheal canula and decanulation. Furthermore differences in muscular activation during mechanical ventilation with regard to body position and changes in minute ventilation during changing body positions. | — |
Countries
Germany
Contacts
Public ContactStephan Walterspacher
Uniklinik Freiburg Abt. Pneumologie
Outcome results
None listed