Preoperative strength and sensorimotor training prior to autologous chondrocyte implantation of the knee joint

Preoperative strength and sensorimotor training prior to autologous chondrocyte implantation of the knee joint - PREHACI

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00003393

Enrollment

Registered

2012-03-20

Start date

2012-06-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M23.99 M94

Interventions

Group 1: The "training group" will perform three sessions a week of strength and sensorimotor training during up to six weeks between the arthroscopic cartilage biopsie and the open knee surgery for

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with isolated symptomatic cartilage defect of the knee joint, planned autologues chondrocyte implantation and signed informed consent

Exclusion criteria

Exclusion criteria: Instability of the knee joint, serious previous surgery, pre-existing neuromuscular conditions, compliance issues (e.g. patient lives too far away from rehabilitation center)

Design outcomes

Primary

Measure	Time frame
Functionality of the knee joint 12 months post-surgery (based on the validated "IKDC - international knee documentation" - 2000 Score (Brittberg et al, JBJS 2003, Niemeyer et al. Arthroscopy, 2010))	—

Secondary

Measure	Time frame
Pain on a visual analoge scale Subjective clinical outcome (Lysholm score and KOOS score) Functionality of the knee in activities of daily living (Chair Rise Test and Stair Climbing Test) Isokinetic muscle strength of knee flexors and knee extensors (Contrex Multijoint System) and measurement of postural control (Posturomed) at the end of the training phase (Pre-OP) as well as six and twelve months post-operatively	—

Measure

Time frame

Pain on a visual analoge scale Subjective clinical outcome (Lysholm score and KOOS score) Functionality of the knee in activities of daily living (Chair Rise Test and Stair Climbing Test) Isokinetic muscle strength of knee flexors and knee extensors (Contrex Multijoint System) and measurement of postural control (Posturomed) at the end of the training phase (Pre-OP) as well as six and twelve months post-operatively

—

Countries

Germany

Contacts

Public ContactAnja HIrschmüller

Univertitätsklinikum Freiburg Department Orthopädie und Traumatologie

anja.hirschmueller@uniklinik-freiburg.de0761 27024010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026