I63.5 A41
Conditions
Interventions
Group 1: Patients with acute ischemic stroke are treated according to clinical practice. Additionally a long-time-ECG and blood-analyses are done.
Sponsors
Klinik für Neurologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Ischemic infarction in the territory of the middle cerebral artery. Age = 18. NIH stroke score NIHSS > 8.
Exclusion criteria
Exclusion criteria: Existing infections at admission. History of previous strokes. Cardiogenic arrhythmias.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development of infection within the subacute phase (day 1-5) of the stroke. Infection is defined according to the PANTHERIS study: - Pneumonia is defined as presence of at least one of the A and one of the B criteria: A) abnormal respiratory examination, pulmonary infiltrates in chest X-Ray; B) productive cough with purulent sputum, microbiological cultures from lower respiratory tract or blood cultures, leukocytosis, and elevation of C-reactive protein (CRP). - Urinary tract infection is defined as the presence of two of the following criteria: fever (>38.0 °C), urine sample positive for nitrite, leucocyturia, and significant bacteriuria. - Infection is also diagnosed if temperature is above 38.0°C on at least 2 determinations with additional leucocytosis and positive blood cultures, but no determined focus. | — |
Secondary
| Measure | Time frame |
|---|---|
| Development of SIRS and severe sepsis in the subacute phase (day 1-5) after Stroke and functional outcome after 3 months. -SIRS (criteria I) is defined according to Guidelines of the German Sepsis Society -Severe Sepsis (criteria I, II and III) is defined according to Guidelines of the German Sepsis Society. - Functional outcome is measured by lethality and neurological scores (modified Rankin Scale, Barthel Index, NIHSS). | — |
Countries
Germany
Contacts
Public ContactDirk Brämer
Klinik für Neurologie
Outcome results
None listed