Diagnosis of early Barrett’s neoplasia and esophageal squamous cell neoplasia by electrical bio-impedance spectroscopy in human tissue

Diagnosis of early Barrett’s neoplasia and esophageal squamous cell neoplasia by electrical bio-impedance spectroscopy in human tissue - -

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00003358

Enrollment

Registered

2011-11-28

Start date

2011-12-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C15.9 K22.7

Interventions

Group 1: Observation group: patient who are planned for endoscopic resection because of known esophageal cancer. Immediately after retrieval the resected specimens were investigated for their electric

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Known esophageal cancer and planned for endoscopic resection

Exclusion criteria

Exclusion criteria: 1. Missing consent / agreement 2. Patient in bad condition for endoscopy or endoscopic resection 3. Patients with coagulopathy or anticoagulative medication which is a contraindication for endoscopy

Design outcomes

Primary

Measure	Time frame
The primary endpoint of the study is to demonstrate that different types of esophageal tissue can be distinguished by their electrical impedance properties. For this purpose the tissue is measured by an electrode directly after resection. The measurement is done over 17 different frequencies in [ohm]. The result is shown as a graph. Subsequently the histological results are compared to the graphs. Finally significant differences are evaluated.	—

Measure

Time frame

The primary endpoint of the study is to demonstrate that different types of esophageal tissue can be distinguished by their electrical impedance properties. For this purpose the tissue is measured by an electrode directly after resection. The measurement is done over 17 different frequencies in [ohm]. The result is shown as a graph. Subsequently the histological results are compared to the graphs. Finally significant differences are evaluated.

—

Secondary

Measure	Time frame
Differences in electrical impedance properties between different stages of early esophageal cancer. The measurments are done in the same way as mentioned at the point of primary outcome	—

Countries

Germany

Contacts

Public ContactOliver Pech

Dr. Horst-Schmidt-Klinik Wiesbaden II. Medizinische Klinik

oliver.Pech@hsk-wiesbaden.de0611432420

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026