J69 J80
Conditions
Interventions
Group 1: ICU-Group: The study analyses the frequency of an aspiration in patients who were just before intubated. Patients receiving at the ICU will be included. After the intubation the secret is ta
Sponsors
Universitätsklinikum Gießen und Marburg
Medizinische Klinik II
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) intubation jsut before 2) medical diagnosis 3) taking of tracheal secret possible within 6 hours after intubation
Exclusion criteria
Exclusion criteria: 1) circulatory insufficiency 2) fiO2> 80% 3) PEEP > 15 mmHg 4) severe lung disease 5) intubation caused by pneumonia 6) stroke in medical history 7) neuromuscular disease 8) pretreatment with antibiotics 9) non invasive ventilation 10) LTX in medical history 11.) gastrectomy in medical history
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Incidence of aspiration after intubation (emergency) - Incidence of Pneumonitis/Pneumonia/ventilator associated pneumonia in case of aspiration - predictive value of detection of pepsin and bile acids in the tracheal secretion (diretly after intubation) vs. standard (suspicion of aspiration, noticed aspiration). | — |
Secondary
| Measure | Time frame |
|---|---|
| - distribution of the pH in the oncdensate of breathing gas - distribution of the pH in tracheal liquid/tracheal secret of intubated patients (emergency) - distribution of uric acid in tracheal liquid/tracheal secret of intubated patients (emergency) - distribution of glucose in tracheal liquid/tracheal secret of intubated patients (emergency) - distribution of IL-6 in tracheal liquid/tracheal secret of intubated patients (emergency) | — |
Countries
Germany
Contacts
Public ContactDieter Walmrath
Universitätsklinikum Gießen und Marburg Medizinische Klinik II
Outcome results
None listed