Investigation of clinical, serological and genetic risk factors of severe osteoarthritis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00003334

Enrollment

2000

Registered

2011-11-17

Start date

2012-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M16.0 M19.0

Interventions

Group 1: Patient cohort: Screening for iron overload at study inclusion and serum/DNA sampling for determination of risk factors for development of hip or ankle joint osteoarthritis. Group 2: Control

Eligibility

Sex/Gender

All

Age

18 Years to 69 Years

Inclusion criteria

Inclusion criteria: Patients: Caucasian males and females aged >18 and 18 and <70 years

Exclusion criteria

Exclusion criteria: Patients: Age 69 years and bone fracture as reason for arthroplasty Controls: Age 69 years

Design outcomes

Primary

Measure	Time frame
Identification of patients with hemochromatosis through screening for iron overload.	—

Secondary

Measure	Time frame
Identification of biomarkers for severe hip or ankle joint osteoarthritis. Identification of disease-relevant gene polymorphisms for severe hip or ankle joint osteoarthritis.	—

Countries

Austria

Contacts

Public ContactJochen Zwerina

Ludwig Boltzmann Institut für Osteologie 1. Medizinische Abteilung Hanusch Krankenhaus

jochen.zwerina@osteologie.at004319102186921

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026