healthy volunteers
Conditions
Interventions
Group 1: Healthy volunteers get an ultrasound guided paravetebralblock. After that they have to undergo a MRI examination to evaluate the spread of local anesthetics.
Sponsors
Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
Eligibility
Sex/Gender
Male
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: • Healthy males aged between 18 and 45 years • BMI < 30 kg/m2 • Written informed consent given by volunteers after being provided with detailed information about the nature, risks, and scope of the clinical study as well as the expected desirable and adverse effects of the drug • No legal incapacity and/or other circumstances rendering the subject unable to understand the nature, scope and possible consequences of the study
Exclusion criteria
Exclusion criteria: • Anatomical abnormalities of the thoracic spine identified by physical examination • Spontaneous pneumothorax in the medical history • BMI =31 kg/m2 • Claustrophobia • Use of NSAID during the last 2 weeks • Known allergy or hypersensitivity against mepivacaine or amino-amide local anaesthetics • Participation in another clinical study within the last 4 weeks prior to study • Coagulopathy • Abnormalities in ECG that are considered clinically relevant like AV-block or bradykardia • Unreliability and/or lack of cooperation • Other objections to participate in the study in the opinion of the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRI visulizied evaluation of spread of local anaesthetics after ultrasound guided paravertebral block | — |
Secondary
| Measure | Time frame |
|---|---|
| pharmacodynamic of paravertbral block | — |
Countries
Austria
Contacts
Public ContactDaniela Marhofer
Universitäsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerzterhapie
Outcome results
None listed