Healthy Volunteers
Conditions
Interventions
Group 1: verum - adjustment of the ear electrode at the left ear, transcutaneous vagus nerve stimulation (t-VNS): frequency 25 Hz,adjust stimulation intensity above perception threshold and below pain
Sponsors
cerbomed GmbH
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: healthy volunteers written informed consent form after volunteer information healthy in terms of medical history
Exclusion criteria
Exclusion criteria: anatomical and pathological abnormalities previous eye surgeries any medication (except contraceptives) participation in a clinical study within the last 4 weeks prior inclusion pregnant or breastfeeding women indications that the participant is expected not to comply with the clinical investigation plan (e.g. lacking willingness to cooperate)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| parameters of the pupillary light reflex: initial pupil diameter, relative amplitude, constriction velocity time of measurement: befor t-VNS (PRE), during t-VNS (PERI) and after t-VNS (POST) | — |
Secondary
| Measure | Time frame |
|---|---|
| sensitive sensations (self-evaluation by the volunteer) screening for vegetative symptoms (self-evaluation by the volunteer) number of adverse events / incidents | — |
Countries
Germany
Contacts
Public ContactAndreas Hertlep
cerbomed GmbH
Outcome results
None listed