F60.31
Conditions
Interventions
Group 1: Characterisation of neural response: 20 female patients with BPD
Neurofeedback training: 20 female patients with BPD
-In the first trial arm, 20 patients with BPD will be included. First, bef
Sponsors
Department of Psychosomatic Medicine and Psychotherapy, Central Institute of Mental Health
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of BPD following DSM4. 2. Remitted patients need to fullfill less than 5 DSM4criteria. 3. Healthy controls aged 18-45 without a history of psychiatric disorders.
Exclusion criteria
Exclusion criteria: Exclusion criteria for all participants • Pregnancy • Lifetime diagnosis of psychotic disorder or bipolar I disorder • Major depressive episode at the time of measurement • Substance dependency in the preceding year • Organic brain diseases • Severe medical or neurological condition • Antecedent cranial or brain injuries • Metallic items in or on the body • Left-handedness • Claustrophobia - Chronic non-healing wounds - blood coagulation disorder - medication with marcumar - anamnestic brain lesion - psychotropic medication within the last two weeks Additional criteria for the healthy control group: • Fulfilling more than one DSM IV criterion for BPD • Any psychiatric disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The BOLD response assessed with fMRI will be explored and better characterized. This should enhance the separation between healthy controls and BPD patients | — |
Secondary
| Measure | Time frame |
|---|---|
| We will test the hypothesis that BPD patients are able to learn to control their emotional response by an fMRI neurofeedback training. | — |
Countries
Germany
Contacts
Public ContactChristian Paret
Central Institute of Mental Health
Outcome results
None listed