Consciousness processes in patients with disorders of consciousness/vegetative state

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00003260

Enrollment

Registered

2011-11-22

Start date

2010-02-19

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

minimally conscious state G93.80

Interventions

Group 1: vegetative state - In different fMRI (functional magnetic resonance imaging) paradigms (mental imagery, language comprehension, trace conditioning, emotional empathy, pain perception), we co

Eligibility

Sex/Gender

All

Age

15 Years to 70 Years

Inclusion criteria

Inclusion criteria: vegetative state, minimally conscious state

Exclusion criteria

Exclusion criteria: missing acoustically evoked potentials (AEP), epileptic potentials in electroencephalography (EEG), sedating medication, magnetic resonance imaging (MRI) contraindications

Design outcomes

Primary

Measure	Time frame
measuring of the BOLD signal with fMRI (1,5 T Siemens TIM Symphony Scanner) in 5 different paradigms: - mental imagery - language comprehension - trace conditioning - emotional empathy - pain perception The main goal of this project is to develop a method to find indications for cognitive and emotional conscious perception, including pain perception, in patient with disorders of consciousness.	—

Secondary

Measure	Time frame
Exploring neuronal basics of conscious perception: - conscious perception needs activation in secondary associative brain areas, needs integration of different areas (e.g. thalamus, precuneus) and needs synchronisation of different brain regions.	—

Countries

Germany

Contacts

Public ContactAlexandra Markl

Schön Klinik Bad Aibling

amarkl@schoen-kliniken.de08061-9031949

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026