Perfusion imaging by arterial spin labelling for clinical use in stroke

Perfusion imaging by arterial spin labelling for clinical use in stroke - PEGASUS

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00003198

Enrollment

Registered

2011-08-12

Start date

2011-08-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I65.2 I66.0 I63.2 I63.5

Interventions

Group 1: Patients undergo MRI with ASL and PWI respectively

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: In-patient or out-patient, neurologically or hemodynamically stable state, one of the following cerebrovascular pathologies: High grade stenosis (>70%) of the common carotid artery, High grade stenosis (>70%) of the internal extracranial carotid artery, High grade stenosis (>70%) of the internal intracranial carotid artery, High grade stenosis (>70%) of the middle cerebral artery, proximal part M1, High grade stenosis (>70%) of the middle cerebral artery, distal parts M2/M3.

Exclusion criteria

Exclusion criteria: MR-contraindications, patients with magnetic implants (pacemaker), claustrophobia, clinically unstable status, unability to give informed consent due to aphasia or reduced vigilance, allergic reaction to gadolinium-based contrast agents, renal insufficiency (GFR = 30 ml/min/1,73 m²), pregnancy

Design outcomes

Primary

Measure	Time frame
CBF (crebral blood flow) in an outlined region of interest (ROI) measured by ASL (arterial spin labelling) and PWI (perfusion weighted imaging)	—

Countries

Germany

Contacts

Public ContactJan Sobesky

CSB-Centrum für Schlaganfallforschung

jan.sobesky@charite.de030 450 560 010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 2, 2026