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Evaluation of Ultrahigh-Field-MRI at 7 Tesla for Imaging of ischemic lesions, carotid plaque morphology and brain perfusion - 7 UP

Evaluation of Ultrahigh-Field-MRI at 7 Tesla for Imaging of ischemic lesions, carotid plaque morphology and brain perfusion - 7 UP - 7-UP

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00003193
Enrollment
100
Registered
2011-08-12
Start date
2011-08-18
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I63.9 I65.2

Interventions

Group 1: magnetic resonance maging at 3 Tesla and 7 Tesla

Sponsors

Charité Campus Charité Mitte
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: General inclusion criteria: - Stable patient condition not requiring in-hospital treatment - Age: 18 – 80 years - Preserved ability to give informed consent - Informed consent - Legal competence Specific inclusion criteria - sub-project 1: o TIA o Cortical/sub-cortical infarcts - sub-project 2: o internal or communal carotid artery stenosis (>50%) or as shown by Doppler sonography - sub-project 3: o internal carotid artery stenosis (>70%) or occlusion as shown by Doppler sonography

Exclusion criteria

Exclusion criteria: Exclusion criteria: - cardiac pacemaker or any other magnetic implant - every kind of metallic or electro-(magnetic) implant - pregnancy and breastfeeding period - claustrophobia - chronic or episodic vertigo - diseases of the retina (e.g. retinal detachment or macula degeneration)

Design outcomes

Primary

MeasureTime frame
part 1: Number of microinfarcts after clinically proven transient ischemic attack, identified by 7 Tesla magnetic resonance imaging (MRI) in comparison to 3 Tesla MRI part 2: Discriminability of core and cap in carotid plaques at 7 Tesla in comparison to 3 Tesla. part 3: Perfusion measurement by ASL at 7 Tesla in comparison to 3 Tesla.

Countries

Germany

Contacts

Public ContactJan Sobesky

CSB-Centrum für Schlaganfallforschung

jan.sobesky@charite.de030 450 560 010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 24, 2026