THE INFLUENCE OF EPIDURAL ANALGESIA VERSUS PATIENT-CONTROLED INTRAVENOUS ANALGESIA ON THE STRESS RESPONSE AFTER MAJOR SPINE SURGERY (A randomized double blind study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00003192

Enrollment

Registered

2011-07-19

Start date

2007-06-20

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

SPINALFUSION and postoperative pain M43.1

Interventions

Group 1: Levobupivacaine via epidural catheter: after the epidural catheter insertion the patients got 0,125% levobupivacaine in the dosage after Bromage and then 0,125% lev0bupivacaine 0,1ml/kg /h fo

Eligibility

Sex/Gender

All

Age

30 Years to 80 Years

Inclusion criteria

Inclusion criteria: patients between 30-80 years ASA 1-3 spondylolystesis with spinal fusion and instrumentation

Exclusion criteria

Exclusion criteria: mental illness drug addiction renal or hepatic insufficiency spondylodiscitis neurological deficits known allergy to local anesthetics

Design outcomes

Primary

Measure	Time frame
VAS (visuel analog scale) pain score each 6hours for 5 days, analgesics consuption in summary for 5 days, cortisol, blood glucose and cholesterol level before surgery and for 4 postoperative days each day, days day of hospital stay	—

Secondary

Measure	Time frame
peristalsis after 24 hours, side effects, postoperative bleeding, time to first postoperative defecation	—

Countries

Slovenia

Contacts

Public ContactDarja Servicl Kuchler

UKC Ljubljana

darja.kuchler@siol.net+38631314099

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026