Differentiation of mutations in toll-like receptors 2 and 4 and their correlation to the classic and modern infect parameters in critically ill patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00003171

Enrollment

149

Registered

2011-07-08

Start date

2006-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critically ill patients R57.2 A41

Interventions

Group 1: Critically ill patients with TLR2 polymorphisms and occurence of infections or sepsis Group 2: Critically ill patients with TLR4 polymorphisms and occurence of infections or sepsis Group 3: C

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Consecutive intensive care treatment of more than 36 h in three anestesiologically managed intensive care units during serial three months periods

Exclusion criteria

Exclusion criteria: 1. age less than 18 years 2. pregnancy

Design outcomes

Primary

Measure	Time frame
severity of sepsis	—

Secondary

Measure	Time frame
1.duration of mechanical ventilation 2.duration of sepsis, 3. duration of severe sepsis, 4. duration of septic shock, 5. mortality 6. duration of ICU stay 7. time-to-onset of infections	—

Countries

Germany

Contacts

Public ContactKAI Sekretariat

Sekretariat der Univ-Klinik für Anästhesiologie m.S. operative Intensivmedizin Charité Campus Virchow-Klinikum

anaesth@charite.de

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026