cervical cancer C53.9
Conditions
Interventions
Group 1: sentinel lymphadenectomy
Group 2: radical pelvic lymphadenectomy
Sponsors
Charité Campus Charité Mitte
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: - Karnofsky-Index =/> 70, - 18-80 year of age - Cervical cancer diagnosed histologically - FIGO 1a1 L1 V0, FIGO 1a2 L0 or L1 V0 FIGO 1b1 L0 or L1 V0 = 2cm - Signed informed consent form - Patient's willing to cooperate
Exclusion criteria
Exclusion criteria: - Neuroendocrine tumours or tumours of mixed type with neuroendocrine component - Invasion of tumour cells in vascular system (V1) - Pregnancy, breast feeding - Distant metastases - Previous malignant diseases - History of pelvic radiotherapy - Severe medical disorders - Psychiatric diseases, that can interfere with participation and follow-up - HIV infection or AIDS - Drugs addiction - Existing motoric or sensoric polyneuropathy > CTC Grad 1 - impossibility to perform anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Peri- and postoperative morbidity Quality of life judged trough questionnaire EORTC QLQ C-30 (3 months after operation, then yearly till 4 year follow-up) Recurrence-free survival | — |
Countries
Germany, Poland
Contacts
Public ContactSergio Frangini
Klinik für Gynäkologie mit Onkologie Charité Campus Mitte
Outcome results
None listed