Vitrectomy plus Encircling Band vs. Vitrectomy alone for the Treatment of Pseudophakic Retinal Detachment (VIPER)

Vitrectomy plus Encircling Band vs. Vitrectomy alone for the Treatment of Pseudophakic Retinal Detachment (VIPER) - VIPER

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00003158

Enrollment

233

Registered

2011-07-04

Start date

2011-06-30

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pseudophakic retinal detachment H33.0

Interventions

Group 1: Control Group: 20 gauge vitrectomy with gas and without encircling band Group 2: Experimental Group 2: small gauge (23 or 25 gauge) vitrectomy with gas Group 3: Experimental Group 1: 20 gaug

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Age: 18 years or older - Pseudophakic rhegmatogenous retinal detachment not suitable for buckling surgery - Agreement of the patient to participate in the trial - Written informed consent of the patient

Exclusion criteria

Exclusion criteria: • Manifest uveitis • Uncontrolled glaucoma • Active retinal vascular disease • Malignant intraocular eye tumours • History of cataract surgery less than 3 months ago • History of any other intraocular surgery other than cataract surgery • Giant retinal tears • PVR grade B or C • Inability to understand the rationale of this trial or the study aim • Participation in another clinical trial (less than 3 months ago) • Aphakia • Systemic disorders preventing the participation of control examinations during the follow-up • Systemic disorders not compatible with the local periocular or general anesthesia

Design outcomes

Primary

Measure	Time frame
Absence of an indication for any retina reattaching procedure during the follow-up of 26 weeks; such procedures are additional gas injections, additional vitrectomy or additional buckling procedure	—

Secondary

Measure	Time frame
- Visual acuity at the end of follow-up as measured by ETDRS charts - Refractive status - Anatomical situation of the anterior and posterior segment - Retina reattachment rate - Occurrence of PVR - Occurrence of adverse events - Number of retina specific procedures to achieve a stable retinal attachment These data will obtained after 6 months of follow-up.	—

Countries

Germany, United Kingdom

Contacts

Public ContactPeter Walter

Universitätsklinikum Aachen, AÖR - Medizinische Fakultät der RWTH

augenklinik@ukaachen.de+49 (0)241 8088191

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 4, 2026