G24
Conditions
Interventions
Group 1: Patients with dystonia without deep brain stimulation
Examination:
H2O-positron emission tomography (PET) with active and passive finger movement and simultaneous EMG-recording at one timepo
Sponsors
Uniklinik Köln
Klinik für Neurologie
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: - male or female patients with cervical or segmental dystonia with or without deep brain stimulation in the globus pallidus internus - diagnosis has to be confirmed with the clinical course and a neurological examination - dystonia has to be bearable after switching the deep brain stimulation
Exclusion criteria
Exclusion criteria: - no preoperative coregistered cranial magnetresonancetomography in case of patients with deep brain stimulation - patients with other neurological disorders (e.g. epilepsia, stroke, Alzheimer's dementia) - life-threatening diseases - severe psychiatric disorders - obvious premorbid mental deficits - pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes in the blood flow in H2O-PET between the following conditions/groups: 1. patients in the rest-condition with and without deep brain stimulation 2. patients in the rest-condition with and without dystonia 3. patients with dystonia and deep brain stimulation in the active and passive movement condition | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the muscular oscillations in the EMG in the following conditions/groups: 1. patients in the rest-condition with and without deep brain stimulation 2. patients in the rest-condition with and without dystonia 3. patients with dystonia and deep brain stimulation in the active and passive movement condition | — |
Countries
Germany
Contacts
Public ContactLars Timmermann
Uniklinik Köln Klinik für Neurologie
Outcome results
None listed