E78.9
Conditions
Interventions
Group 1: Daily consumption of 250 mL milk, enriched with 3 g milk phospholipids, during 7 weeks
Group 2: Daily consumption of 250 mL milk, enriched with 3 g soy phospholipids, during 7 weeks
Sponsors
Max Rubner-Institut Bundesforschungsinstitut für Ernährung und Lebensmittel
Eligibility
Sex/Gender
Male
Age
50 Years to 76 Years
Inclusion criteria
Inclusion criteria: Overweight male volunteers, age 50- 76 years, non-smokers; written informed consent
Exclusion criteria
Exclusion criteria: - fasting glucose levels >120 mg/dl - Known metabolic or gastro-intestinal diseases, which affect the absorption, metabolism or excretion of food or food components; - Known allergy against milk or soy components - intake of supplements which might affect the parameters tested - intake of drugs which might affect the parameters tested - intestinal tract surgery or corticoid steroid treatment within the last 3 months - Inability to understand and to comply with the study protocol; - unusually high consumption of milk or dairy products - occurrence of acute gastrointestinal disorders during intervention - Occurrence of other unexpected events with relevance for the study outcome - withdrawal of consent to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ratio of total zu HDL-cholesterol in serum (after 7 weeks) | — |
Secondary
| Measure | Time frame |
|---|---|
| Further parameters of lipid metabolism(triglycerides, LDL-cholesterol), glucose metabolism (glucose, insulin), hepatic metabolism (GOT, GGT, GPT), thiol metabolism (glutathione, homocysteine), inflammation (CRP, endothelial adhesion molecules) and body composition after 7 weeks intervention | — |
Countries
Germany
Contacts
Public ContactAnne Weiland
Max Rubner-Institut Bundesforschungsinstitut für Ernährung und Lebnsmittel
Outcome results
None listed