Progression of the dopaminergic deficit of akinetic-rigid and tremordominant Parkinson's Disease patients

Progression of the dopaminergic deficit of akinetic-rigid and tremordominant Parkinson's Disease patients - ProDDAT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00003110

Enrollment

Registered

2011-06-20

Start date

2011-06-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20

Interventions

Group 1: Tremordominant Parkinson's disease patients The following test are done: - UPDRS in the ON and OFF medication state - neuropsychological testing with BDI-2, DemTect, PANDA, Hypomania-questio

Eligibility

Sex/Gender

All

Age

30 Years to 80 Years

Inclusion criteria

Inclusion criteria: - male or female patients with the clinical diagnosis of an idiopathic Parkinson syndrome - previous FP-CIT-SPECT 2-5 years before - patient in the age between 30 and 80 years - patients have to given written informed consent

Exclusion criteria

Exclusion criteria: - patients with another disease which leads to cognitive impairment (tumor, vascular incidents, etc.) - patients with depression or dementia

Design outcomes

Primary

Measure	Time frame
visual type in the dopamine transporter single photon emission computertomography (DaT-Scan)	—

Secondary

Measure	Time frame
United Parkinson's Disease Rating Scale (UPDRS) part III: assessment of parkinsonian symptoms Beck-Depression-Inventory-2: assessment of depression DemTect: assessment of dementia Parkinson Neuropsychiatric Dementia assessment (PANDA): assessment of Parkinson's disease related dementia Hypomania-questionnaire: assessment of hypomania Barrett Impulsiveness Scale: assessment of impulsiveness Nonmotor-symptoms Questionnaire	—

Measure

Time frame

United Parkinson's Disease Rating Scale (UPDRS) part III: assessment of parkinsonian symptoms Beck-Depression-Inventory-2: assessment of depression DemTect: assessment of dementia Parkinson Neuropsychiatric Dementia assessment (PANDA): assessment of Parkinson's disease related dementia Hypomania-questionnaire: assessment of hypomania Barrett Impulsiveness Scale: assessment of impulsiveness Nonmotor-symptoms Questionnaire

—

Countries

Germany

Contacts

Public ContactLars Timmermann

Uniklinik Köln Klinik für Neurologie

lars.timmermann@uk-koeln.de0221/4787494

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026