prospective comparison of microcirculation during surface- vs: endovascular cooling after successful treatment reanimation

prospective comparison of microcirculation during surface- vs: endovascular cooling after successful treatment reanimation - OEKER-Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00003107

Enrollment

Registered

2011-05-30

Start date

2010-10-22

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I46.0

Interventions

Group 1: Surface cooling method with Thermowrap system (airflow system via blankets) Microcirculation measurement: 1. at admission, 2. After receiving target bodytemperature of 33C (24 h), 3. after r

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: patients after successful resuscitation

Exclusion criteria

Exclusion criteria: Pregnancy, contraindication to cool, living will, morbid obesity (BMI> 40)

Design outcomes

Primary

Measure	Time frame
Analysis of the microcirculation by means of NIRS (near infrared spectroscopy) in combination with occlusion of an upper arm (VOT, vascular occlusion test), analysis of capillary refill time in extremities	—

Secondary

Measure	Time frame
30 days mortality, cooling times, Neurological Outcome, complications, collection of clinical outcome parameters such as SOFA score, APACHE II, Glasgow Coma Scale (GCS) and Glasgow Outcome Score (GOS) and as part of standard bloodsamples biochemical studies to evaluate the consecutive end-organ damage and the activation of plasma coagulation system	—

Countries

Germany

Contacts

Public ContactHans-Jörg Busch

Uniklinik Freiburg, Medizinische Klinik, ,

hansjoerg.busch@uniklinik-freiburg.de0761 270 3401

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026