Effect of an interdisciplinary multimodal long-term weight reduction program on left ventricular diastolic function in morbid obesity

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00003087

Enrollment

520

Registered

2011-06-15

Start date

2009-07-20

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I50.12 E66.9

Interventions

Group 1: Successful participation in the Optifast-52 weight reduction program (Nestle Healthcare). The Optifast -52 program is a standardized multimodal program, encompassing dietetic treatment, physi

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: BMI>30 kg/m2; constant body weight during the last 3 months

Exclusion criteria

Exclusion criteria: pregnancy, consuming illnesses, addiction

Design outcomes

Primary

Measure	Time frame
Improvement of diastolic function 1 year after weight reduction	—

Secondary

Measure	Time frame
1. predictors of left ventricular diastolic dysfunction in obesity and the metabolic syndrome 2. predictive capability of heart failure biomarkers (NTproBNP, GDF-15) in severe obesity	—

Countries

Germany

Contacts

Public ContactAndrea Baessler

Klinik und Poliklinik für Innere Medizin II, Universitätsklinikum Regensburg

andrea.baessler@klinik.uni-regensburg.de0941-9447299

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026