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Early diagnosis of sepsis-related hepatic dysfunction and its prognostic impact on survival: a prospective study with the LiMAx test

Early diagnosis of sepsis-related hepatic dysfunction and its prognostic impact on survival: a prospective study with the LiMAx test - LiSep-Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00003085
Enrollment
30
Registered
2011-09-02
Start date
2011-09-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41 K72

Interventions

Group 1: Estimation of the liver function in septic patients with LiMAx-Test

Sponsors

Charitè - Universitätsmedizin Berlin - Campus Virchow Klinik für Allgemein-, Viszeral- und Transplantationschirurgie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Bacterial Sepsis Inform consent present

Exclusion criteria

Exclusion criteria: Allergy against ICG or Methacetin Chemotherapy in the last 8 weeks Immunosuppression (Equivalent of Cortison >5mg) Advanced liver dysfunction prior to actual disease Any organ transplantation HIV Pregnancy, breast feeding Absent inform consent Factors, limitating the ability of patients to cooperate during study (e. g. reduced mental function, drug abuse)

Design outcomes

Primary

MeasureTime frame
Correlation between result of the Maximal Liver Function Capacity Test (LiMAx-Test) the mortality rate

Secondary

MeasureTime frame
Comparison of the result of the Maximal Liver Function Capacity Test (LiMAx-Test) with the Indocyaningreen plasmadilution rate and other parameter for assessment of the liver function (transaminases, bilirubine, coagulation-tests, zxtokines) Length of stay in intensive care unit Lenght of stay in hospital

Countries

Germany

Contacts

Public ContactMagnus Kaffarnik

Charite - Universitätsmedizin Berlin, Campus Virchow Klinik für Allgemein, Viszeral- und Transplantationschirurgie

magnus.kaffarnik@charite.de+49(0)30450652235

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026