C61
Conditions
Interventions
Group 1: DCE-MRI protocol will be performed before and 12 months after completion of salvage-radiotherapy. DCE-MRI are acquired on 1.5-Tesla systems each equipped with surface phased array. Imaging of
Sponsors
Universitätsklinikum Freiburg
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Patients with a history of prostate carcinoma and status after radical prostatavesikoektomy with biochemical (PSA) recurrence (definition of PSA recurrence: three consecutive rising PSA values ??above the nadir,> 6 months after surgery) - Are not receiving anti-hormonal therapy - Who have no impairment of renal function and no contraindications for the whole-body MRI - Consent to participate in the study after detailed explanation of previous and written consent
Exclusion criteria
Exclusion criteria: - Clinical and imaging suspicion of lymph node metastases or distant metastases - State of pelvic radiotherapy - Known allergy to contrast agent gadolinium-chelates - Renal (filtration rate <40 ml / min) - After kidney or liver transplant - Start an anti-hormonal therapy prior to study entry - Contraindications to MR studies (pacemakers, metallic clips after magnetizable brain or heart surgery, cochlear implants, metallic foreign body in the eye, insulin pumps, etc.). - Ferromagnetic intracorporeal debris - Previous SM / AICD implantation
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| PSA progression after salvage radiotherapy (Re-recurrence) | — |
Primary
| Measure | Time frame |
|---|---|
| Sensitivity and specificity of MRI for the detection of local recurrence in treatment planning | — |
Countries
Germany
Contacts
Public ContactHans Christian Rischke
Universitätsklinikum Freiburg
Outcome results
None listed