Respiratory muscle strength in pulmonary fibrosis

Respiratory muscle strength in pulmonary fibrosis - Fibremus

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000817

Enrollment

Registered

2011-05-02

Start date

2009-02-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J84.1

Interventions

Group 1: Fibrosis-patients: Assessment of respiratory muscle strength (Pimax, P0.1, Sniff, Twitch mouth pressure), 6minute walking test, bodyplethysmography, laboratory parameters (CCl18, CRP) Group 2

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: histologically assessed pulmonary fibrosis in the patient group

Exclusion criteria

Exclusion criteria: Patients: other lung diseases right heart failure diabetes mellitus neuromuscular diseases Control subjects Lung diseases severe cardiac disease diabetes mellitus neuromuscular diseases

Design outcomes

Primary

Measure	Time frame
One-time assessment of twitch mouth pressure after bilateral anterior magnetic stimulation as a measure of diaphragmatic strength using an automated shutter-occluded spirometer.	—

Secondary

Measure	Time frame
One-time assessment of global respiratory muscle strength (PImax), respiratory drive (P0.1) and Sniff pressure at the mouth using an automated shutter-occluded spirometer. Correlation of respiatroy muscle strength with performance in the 6min walking test and diseas-specific laboratoy parameters (CCL18).	—

Countries

Germany

Contacts

Public ContactStephan Walterspacher

Uniklinik Freiburg Abt. Pneumologie

stephan.walterspacher@uniklinik-freiburg.de+49 761 270-74070

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026