Flow in Coronary Arteries -Wall Shear Stress as Coronary Risk.

Flow in Coronary Arteries -Wall Shear Stress as Coronary Risk. - Non-invasive CFD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000791

Enrollment

Registered

2011-12-05

Start date

2013-11-17

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease I25

Interventions

Group 1: A MRI will be done in patients with suspected ischemia. In case of a positive test confirming ischemia the patient will be included and a cardiac catheterization will be performed with the op

Eligibility

Sex/Gender

All

Age

21 Years to No maximum

Inclusion criteria

Inclusion criteria: Adult patients with clinically suspected ischemia and diagnostic magnetic resonance imaging

Exclusion criteria

Exclusion criteria: Contraindications against magnetic resonance imaging Relative contraindications against catheterization and intracoronary imaging.

Design outcomes

Primary

Measure	Time frame
Agreement of predicted group adherence (negative, expansive normal remodeling) between MRI based and catheterization- based diagnostic flow simulation studies.	—

Secondary

Measure	Time frame
1) Comparison of anatomical data and flow data for the right coronary artery between magnetic resonance imaging and catheterization-based data acquisition and of wall shear stress calculations based on flow-simulations using catheterization based data and MRI derived data. 2) Exploratory investigations regarding the impact of changes in wall shear stress and derived parameters on events during follow-up and findings in magnetic resonance imaging after one year. Important goal is the collection of data for planning future investigations of coronary flow as risk factor in coronary arteries.	—

Measure

Time frame

1) Comparison of anatomical data and flow data for the right coronary artery between magnetic resonance imaging and catheterization-based data acquisition and of wall shear stress calculations based on flow-simulations using catheterization based data and MRI derived data. 2) Exploratory investigations regarding the impact of changes in wall shear stress and derived parameters on events during follow-up and findings in magnetic resonance imaging after one year. Important goal is the collection of data for planning future investigations of coronary flow as risk factor in coronary arteries.

—

Countries

Germany

Contacts

Public ContactErnst Wellnhofer

Deutsches Herzzentrum Berlin

wellnhofer@dhzb.de00493045932498

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026