Urinary l-lactate/creatinine ratio in neonatala asphyxia for the early detection of hypoxic-ischemic encephalopathy.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000774

Enrollment

Registered

2011-03-29

Start date

2004-01-12

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

P21

Interventions

Group 1: study group: Neonates not older than 24 h with Severe perinatal Asphyxia with organ failure Group 2: control group: Neonates not older than 24 h severe asphyxia without consecutive organ f

Eligibility

Sex/Gender

All

Age

0 Days to 3 Days

Inclusion criteria

Inclusion criteria: Newborns were recruited prospectively if they met any of the following criteria: - cord blood pH <7.15 - base excess <-10 mmol/l - Apgar score at 5 minutes <6 - cardio-pulmonary resuscitation.

Exclusion criteria

Exclusion criteria: maternal drug abuse, severe congenital malformation

Design outcomes

Primary

Measure	Time frame
Urinary lactate/creatinine by massspectrometry	—

Secondary

Measure	Time frame
comparison between D and L-Lactate correlation of urinary lactate to APGAR and umbilical cord pH	—

Countries

Germany

Contacts

Public ContactMarcus Krueger

Universitätsklinikum Freiburg

marcus.krueger@uniklinik-freiburg.de00497612704300

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026