Impact of a postoperative short term NIV on lung function and oxygenation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00000751

Enrollment

Registered

2011-04-06

Start date

2009-01-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients in the postoperative period E66.0

Interventions

Group 1: Short term NIV (noninvasive ventilation) during PACU (Post-anesthesia care unit) stay commenced immediately after surgery Group 2: Control group, no active therapy - passive oxygen delivery v

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Obesiti BMI >30, minor surgery procedures using a tracheal intubation for airway management

Exclusion criteria

Exclusion criteria: preexisting pulmonary deseases, Major surgery

Design outcomes

Primary

Measure	Time frame
Postoperative spirometric lung function (Measured parameters FEV1 - forced expiratory lung volume/1s , FVC-forced vital capacity ,MEF25-75 - mid expiratory flow 25-75%, PEF - peak expiratory flow, FIVC - forced inspiratory vital capacity, PIF - peak inspiratory flow) measurements at the respective fixed time points after achieving a fast track score >10 (White et al).T0h= after achieving a fast track score >10, all patients included have to achieve a fast-track score >10 within 20 minutes after surgery. All further time points are fixed time points after surgery.T1h = 1 hour after surgery, T2h = 2 hours after surgery, T6h = 6hours after surgery after first mobilisation of the patients. T24h= 24 hours after surgery	—

Measure

Time frame

Postoperative spirometric lung function (Measured parameters FEV1 - forced expiratory lung volume/1s , FVC-forced vital capacity ,MEF25-75 - mid expiratory flow 25-75%, PEF - peak expiratory flow, FIVC - forced inspiratory vital capacity, PIF - peak inspiratory flow) measurements at the respective fixed time points after achieving a fast track score >10 (White et al).T0h= after achieving a fast track score >10, all patients included have to achieve a fast-track score >10 within 20 minutes after surgery. All further time points are fixed time points after surgery.T1h = 1 hour after surgery, T2h = 2 hours after surgery, T6h = 6hours after surgery after first mobilisation of the patients. T24h= 24 hours after surgery

—

Secondary

Measure	Time frame
blood gas analysis of paO2 paCo2 and AaDO2 at the fixed time points T0h, T1h and T2h	—

Countries

Germany

Contacts

Public ContactMartin Zoremba

Uniklinikum Marburg

zoremba@med.uni-marburg.de064215865985

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 29, 2026