Sensitivity and specifity of surrogat markers for diagnostics of heparin-induced thrombocytopenia type II (HIT II)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000726

Enrollment

500

Registered

2011-02-16

Start date

2011-02-04

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D69.6

Interventions

Group 1: comparison of patients with positive and negative HIT II diagnostics, no intervention

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: all patients, for whom HIT II diagnostics is requested at the Department of Clinical Chemistry

Exclusion criteria

Exclusion criteria: requests from outside the university hospital; necessity of additional blood drawing

Design outcomes

Primary

Measure	Time frame
cut-off of soluble fibrin as negative predictor (>95%) of HIT II	—

Secondary

Measure	Time frame
- cut-offs for IPF, d-dimers, fibrin monomers, prothrombin fragments in HIT II patients and diagnostic specifity - correlation of these parameters - specifity of combinations of these parameter - association of soluble fibrin or fibrin monomers with anticoagulation and thrombocytopenia - predictive value of the parameters for thrombembolic events within 30 day after request for test	—

Countries

Germany

Contacts

Public ContactUlrich Geisen

Universitätsklinikum Freiburg, Abt. Klinische Chemie

ulrich.geisen@uniklinik-freiburg.de+49/761-270 3516

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 5, 2026