Impact of alveolar target-volume in noninvasive positive pressure ventilation of patients with chronic obstructive pulmonary disease: A randomized cross-over trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00000714

Enrollment

Registered

2011-02-24

Start date

2011-01-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J96.1 J44.81 J44.80

Interventions

Group 1: ventilation with own respirator in pressure controlled mode Group 2: ventilation in iVAPS mode

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: patients with chronic respiratory failure using noninvasive ventilation for more than 2 months, stable illness

Exclusion criteria

Exclusion criteria: acute exazerbation (> 2 of the following signs: infiltrates in chest x-ray, increase of CRP or leukocytes, yellow or green sputum, fever)

Design outcomes

Primary

Measure	Time frame
daily measured subjective quality of sleep using visual analogue scale	—

Secondary

Measure	Time frame
ventilated hours during the 6-weeks intervall subjective evaluation of the therapy concerning morning recreation, application of pressure, mask position PaO2 PaCO2 pH BE	—

Countries

Germany

Contacts

Public ContactEmelie Ekkernkamp

Universitätsklinik Freiburg, Abteilung Pneumologie

emelie.ekkernkamp@uniklinik-freiburg.de07612703706

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026