Hemodynamics during pacing-induced left bandle branch block compared to biventricular pacing

Hemodynamics during pacing-induced left bandle branch block compared to biventricular pacing - SILVER-BI

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00000667

Enrollment

Registered

2011-01-25

Start date

2011-01-21

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I50.9 I50.14

Interventions

Group 1: right- and bi-ventricular pacing

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Standard indication for an electrophysiology study (EPS) • Heart failure NYHA II-IV despite optimal medical treatment • Left ventricular ejection fraction less than or equal to 40% • Narrow QRS-complex (less than 120ms)

Exclusion criteria

Exclusion criteria: • Underage patients • Pregnant women • Patients who attend other studies at the same time • Persistant or permanent atrial fibrillation

Design outcomes

Primary

Measure	Time frame
The increase of dP/dt during bi-ventricular stimulation is measured via an intracardiac pressure-wire. These measurements are performed during the procedure.	—

Secondary

Measure	Time frame
Cardiac output is determined under different V-V-intervals. For these measurements an intracardiac pressure-wire is used.	—

Countries

Germany

Contacts

Public ContactJürgen Biermann

UNIVERSITÄTSKLINIKUM FREIBURG Medizinische Klinik III Kardiologie und Angiologie

juergen.biermann@uniklinik-freiburg.de+49 761 270 3401 0

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026