Total brain perfusion 320 row CT application in acute, subacute and chronic stroke

Total brain perfusion 320 row CT application in acute, subacute and chronic stroke - TOPAS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000616

Enrollment

Registered

2011-01-03

Start date

2011-05-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischaemic Stroke I63

Interventions

Group 1: In the trail patients with acute, subacute and chronic stroke will be included. After inclusion patients should be imaged as fast as possible with 320 row pCT and pw/dw MRI (time between bou

Eligibility

Sex/Gender

All

Age

50 Years to 85 Years

Inclusion criteria

Inclusion criteria: -->Acute (symptomonset subacute stroke (symptomonset >24h-14d) --> chronic stroke (> 14d) --> Age 50-85 --> NIHSS =2

Exclusion criteria

Exclusion criteria: --> contraindications for MRI (e.g. magnetic implants, pacemaker) --> claustrophobia --> critical clinical condition --> missing capacitiy to contract (loss of conciousness, severe aphasia) --> infarct in the posterior circulation --> hypothyreosis --> allergic reaction on contrast agent --> renal failure (creatinin clearance >0,9 mg/dl)

Design outcomes

Primary

Measure	Time frame
This study is a pilot study. Thus, the exact definition of endpoints is not possible. After the imaging procedures the trail is finished. The definition of hypoperfusion on 320 row pCT will be compared to dw/pw MRI in a voxel based analysis	—

Secondary

Measure	Time frame
Not applicable for this trial	—

Countries

Germany

Contacts

Public ContactKatharina Stengl

CSB-Centrum für Schlaganfallforschung

katharina.stengl@charite.de030 450 560 640

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026