healthy volunteers
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age: 16 years Gender: female Pubertal status late-pubertal (Self-rating scale for pubertal development according to Carskadon: Score = 7) Right-dominant hand Students at Gymnasium Normal and stable sleep behaviour Normal or corrected-to-normal vision Girls: have to be in the follicular phase of the menstrual cycle (days 5-15) on test day. Girls on oral contraceptives will be studied within the first three weeks of their pill cycle (menstruation calendar).
Exclusion criteria
Exclusion criteria: Not able to provide informed consent and unsufficient knowledge of German language (Grade for German below 4) Current or past mental illness (lifetime) Mental illnesses in first degree relatives Epilepsy or other chronic diseases Regular intake of centrally acting medication Current or past legal and illegal drug abuse or dependence No regular use of alcohol Excessive use of caffeine (>300 mg or 3 cups of coffee/day) Pregnancy (Urinetest) Claustrphobia Smoker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percent improvement in mirror tracing draw time, Percent recall in the word pair associate task, reduction in ms of the Stimulus Onset Asynchrony (SOA) in the texture discrimination task (TDT) from the test to retest condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary analyses include the correlations between EEG sleep variables (amount of slow wave sleep (SWS) and REM sleep, number of sleep spindles) and memory performance, and cortisol levels. | — |
Countries
Germany
Contacts
Universitätsklinikum Freiburg, Abteilung für Psychiatrie und Psychotherapie