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Polypharmacy as a result of multiple chronic conditions of older people: rational therapy with the new FORTA classification?

Polypharmacy as a result of multiple chronic conditions of older people: rational therapy with the new FORTA classification?

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00000531
Enrollment
400
Registered
2010-09-15
Start date
2011-11-28
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

eligible for the study are patients of a geriatric unit with numerous co-morbid conditions.

Interventions

Group 1: Review and adjustment of medication according to the FORTA criteria Group 2: Continue the medication according to guidelines and Good Medical Practice

Sponsors

Institut für klinische Pharmakologie Mannheim Universität Heidelberg
Lead Sponsor
Kliniken Essen Mitte Zentrum für Altersmedizin
Collaborator

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: informed consent given, stable clinical condition, no palliative condition

Exclusion criteria

Exclusion criteria: missing informed consent, palliative clinical condition, unstable clinical condition, need of intensive care unit (ICU) treatment

Design outcomes

Primary

MeasureTime frame
The FORTA classification encompasses four classes of drugs. Drugs with well documented evidence for the elderly constitute the classes A and B, drugs with limited evidence constitute the class C. Drug of the class D should be avoided in the elderly. The aim of the study is the statistical measurement of the difference in the distribution of medication at discharge according to the four classes of FORTA between the two patient groups (clusters).

Secondary

MeasureTime frame
Statistically comparisone of the the two clusters regarding Number of untreated disease Number of diseases overtreated

Countries

Germany

Contacts

Public ContactHelmut Frohnhofen

Kliniken Essen Mitte Zentrum für Altersmedizin

h.frohnhofn@kliniken-essen-mitte.de0201-17423001

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 28, 2026