Feasibility of prehabilitation before major abdominal surgery
Conditions
Interventions
Group 1: Diagnostic cardiopulmonary exercise testing (1) and additional preoperative high-intensity-interval-training (HIIT) (2)
1: a) one month preoperatively and b) two days preoperatively
2: High-intensity-interval-training (HIIT) over 1 month preoperatively
2 x per week at minimum
b) no training postoperatively
Group 2: Diagnostic cardiopulmonary exercise testing
Sponsors
Uniklinik Köln
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients scheduled for intraabdominal gynecological surgery, female sex, willingness to perform exercise and written informed consent.
Exclusion criteria
Exclusion criteria: Recent history (< three months prior to screening) of myocardial infarction, new or unstable angina, venous thromboembolism or chronic deep vein thrombosis, cerebrovascular accident or transit ischaemic attacks, ongoing pregnancy, scheduled surgery too early to enable preoperative trial participation, and the inability to exercise above anaerobic threshold (self-reported, evident from patient history, or detected by first Cardiopulmonary Exercise Testing after initial trial participation).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility of a four-week prehabilitation program with intensive interval training and the associated increase in physical performance. | — |
Secondary
| Measure | Time frame |
|---|---|
| Increase in the number and functionality of endothelial progenitor cells in the peripheral blood. | — |
Countries
Germany
Contacts
Public ContactRobert Schier
Uniklinik Köln
Outcome results
None listed