Quality of sleep during noninvasive positive pressure ventilation with high inspiratory pressures in patients with stable hypercapnic COPD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00000520

Enrollment

Registered

2010-10-05

Start date

2008-02-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Other specified chronic obstructive pulmonary disease FEV unspecified ?

Interventions

Group 1: high-intensity noninvasive positive pressure ventilation (pressure controlled ventilation with high inspiratory pressures) Group 2: high-intensity noninvasive positive pressure ventilation (p

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: COPD GOLD stage IV with home mechanical ventilation

Exclusion criteria

Exclusion criteria: acute exazerbation

Design outcomes

Primary

Measure	Time frame
Polysomnographic assessment of NREM sleep stage 3 and 4 during nighttime noninvasive ventilation. Ventilation with high and low pressures is carried out on two consecutive days.Ventilation with high and low pressures is carried out on two consecutive days. Difference in sleep quality? ?	—

Secondary

Measure	Time frame
Polysomnographic assessment of REM sleep, blod gas analysis; both assessed during nighttime noninvasive ventilation	—

Countries

Germany

Contacts

Public ContactMichael Dreher

Universitätsklinikum Aachen

mdreher@ukaachen.de+492418035881

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 29, 2026