Inflammatory cytokines in sera and bronchoaleveolar lavage as prognostic marker in children with severe respiratory failure

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000510

Enrollment

Registered

2010-09-16

Start date

2010-09-21

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J96

Interventions

None listed

Eligibility

Sex/Gender

All

Age

1 Months to 17 Years

Inclusion criteria

Inclusion criteria: Mechanically ventilated children aged >1 month to < 18 years who need bronchoalveolar lavage and blood examination due to medical and theraeuptical reasons. For example, BAL might be needed for microbiological testing and a directed antibiotical therapy. As control group we will include patients who undergo bronchoscopy with bronchoalveolar lavage and blood examination but are not mechanically ventilated. These patients need diagnostic procedures to exclude laryngomalacy and get more information on unexplained tracheal cough.

Exclusion criteria

Exclusion criteria: Severe concomitant diseases, like congenital lung malformation, immune deficiency or increased cerebral pressure and instability of cardiovascular circulation after manipulation.

Design outcomes

Primary

Measure	Time frame
Correlation of inflammatory cytokines in BAL and sera with severity of pediatric acute respiratory syndrome (days of ventilation, oxygenation index).	—

Secondary

Measure	Time frame
Correlation of inflammatory cytokines in BAL and sera with severity of pediatric acute respiratory -depending of the cause of ARDS	—

Countries

Germany

Contacts

Public ContactHolger Meinicke

ZKJ

holger.meinicke@uniklinik-freiburg.de0761-2704301

Outcome results