Circadian cardiovascular regulation in pregnancy - new aspects of risk assessment and prevention

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00000496

Enrollment

825

Registered

2010-08-25

Start date

2010-11-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Z35

Interventions

Group 1: The selection criteria heart rate variability (HRV), baro receptor sensitivity (BRS) as well as blood pressure variability (DBP) are determined in woen wirth abnormal cardiovascular reactivit

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: pregnant women, 18-24 weeks of gestation, pathologic uterine flow

Exclusion criteria

Exclusion criteria: BMI > 30, multiple gestation, fetal malformations, structural or chromosomal aberrations, preexisting hypertension, renal disease

Design outcomes

Primary

Measure	Time frame
A reduced heart-rate variability, which is caused by sleep-apnoe is predictive for the later onset of preeclampsia - as determined by polysomnographic measurement	—

Secondary

Measure	Time frame
reduced heart rate variability in patients who later develop preeclampsia	—

Countries

Germany

Contacts

Public ContactWolfgang Henrich

Charité Universitätsmedizin Berlin Klinik für Geburtsmedizin

wolfgang.henrich@charite.de030450664173

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026