Regulation of the Receptor of Advanced Glycation Endproducts in Sepsis after Polytraumatization

Regulation of the Receptor of Advanced Glycation Endproducts in Sepsis after Polytraumatization - RiSaP

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000480

Enrollment

100

Registered

2010-07-21

Start date

2010-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T07 A41.9

Interventions

None listed

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Polytraumatization with ISS>16

Exclusion criteria

Exclusion criteria: terminal kidney insufficiency, Diabetes mellitus, rheumathoid arthritis, Morbus Alzheimer, inflammatory bowel disease, artherisclerosis with previous myocardial ischemia, myocardial bypass surgery, stent implantation surgery

Design outcomes

Secondary

Measure	Time frame
28-day-mortality	—

Primary

Measure	Time frame
Prevalence of SIRS/sepsis (ACCP/SCCM consensus conference) during the initial 9 days after polytraumatization - aim is to examine the correlation between expression and abundance of the receptor on the cell membran and in the patients plasma with the development of a systemic inflammatory complication	—

Countries

Germany

Contacts

Public ContactChristoph Lichtenstern

Klinik für Anästhesie, Intensivmedizin und Schmerztherapie

christoph.lichtenstern@chiru.med.uni-giessen.de0641/9944401

Outcome results