MuKiS - mother-child-sports - a study to evaluate the impact of exercise on maternal metabolism and fetal development in women with gestational diabetes

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00000465

Enrollment

Registered

2010-06-30

Start date

2009-05-29

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

O24.4

Interventions

Group 1: physical activity intervention: under professional supervision, two times a week, 45 minutes, heart rate, alternately walking and bicycle ergometry. Nutrition: Diet therapy according to the d

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Women who are diagnosed with gestational diabetes (gestational diabetes according to the guidelines of the AG Diabetes and pregnancy DDG 2003), • confinement during the 24th and 30th Week of pregnancy • > 18 years of age • Written permission

Exclusion criteria

Exclusion criteria: • disease of the heart, circulatory or kidney • Arterial hypertension or hypertensive disease of pregnancy • multiple pregnancy • Acute systemic diseases or infections • cervical incompetence, cerclage • Premature labor in current pregnancy • placenta praevia after the 26th Week of pregnancy • contraindications, which do not permit participation in moderate physical activity

Design outcomes

Primary

Measure	Time frame
The present project should investigate, if maternal metabolism and child development get positively influenced by increasing physical activity during pregnancy in women with gestational diabetes. The project is carried out first as a pilot study in 60 women. When all 60 women are recruited, in about two years, the evaluation will begin. At the same time should also be assessed the feasibility of a sports intervention in this patient population. Target parameters for a viable and successful sports intervention are: 1) High participation rates and compliance, regardless of nationality and social factors 2) to increase the well-being and spontaneous physical activity (mood questionnaire: Visit 0: 29-30. pregnancy week, Visit 1: 38-39 pregnancy week, Visit 3: 4 weeks postpartum) 3) improving the performance / handling of pregnant women (reduction of resting heart rate, cycle ergometer test according to WHO criteria, measurement of heart rate, Visit 0: 29-30. week of pregnancy, Visit 3: 4 weeks postpartum) 4) Change of maternal biomarkers by sports Intervention (adipokines, metabolomics, insulin resistance, breath Profile: Visit 0: 29./30. week of pregnancy, Visit 1: 38./39. week of pregnancy, Visit 3: 4 Wochen postpartum) 5) normalization of the fetal abdominal circumference, lower rate of polyhydramnios and Sectioraten, and normalization of birth weight (Fetal Ultrasound Visit 0: 29./30. week of pregnancy. Ultrasound of the child. Visit 2: 4 weeks postpartum) 6) Reduced rate of prenatal fetal macrosomia and cardiac hypertrophy 7) Lower postnatal rate of macrosomia and cardiac hypertrophy. In summary: The aim of the physical activity is to improve performance, and to obtain a positive effect on childbirth. We also assume that the physical activity of the mother has an effect on the development of the child. One of the main goals is the long-term mothers to a lifestyle change to move that through healthy diets and increased physical activity will affect the whole fami	—

Measure

Time frame

The present project should investigate, if maternal metabolism and child development get positively influenced by increasing physical activity during pregnancy in women with gestational diabetes. The project is carried out first as a pilot study in 60 women. When all 60 women are recruited, in about two years, the evaluation will begin. At the same time should also be assessed the feasibility of a sports intervention in this patient population. Target parameters for a viable and successful sports intervention are: 1) High participation rates and compliance, regardless of nationality and social factors 2) to increase the well-being and spontaneous physical activity (mood questionnaire: Visit 0: 29-30. pregnancy week, Visit 1: 38-39 pregnancy week, Visit 3: 4 weeks postpartum) 3) improving the performance / handling of pregnant women (reduction of resting heart rate, cycle ergometer test according to WHO criteria, measurement of heart rate, Visit 0: 29-30. week of pregnancy, Visit 3: 4 weeks postpartum) 4) Change of maternal biomarkers by sports Intervention (adipokines, metabolomics, insulin resistance, breath Profile: Visit 0: 29./30. week of pregnancy, Visit 1: 38./39. week of pregnancy, Visit 3: 4 Wochen postpartum) 5) normalization of the fetal abdominal circumference, lower rate of polyhydramnios and Sectioraten, and normalization of birth weight (Fetal Ultrasound Visit 0: 29./30. week of pregnancy. Ultrasound of the child. Visit 2: 4 weeks postpartum) 6) Reduced rate of prenatal fetal macrosomia and cardiac hypertrophy 7) Lower postnatal rate of macrosomia and cardiac hypertrophy. In summary: The aim of the physical activity is to improve performance, and to obtain a positive effect on childbirth. We also assume that the physical activity of the mother has an effect on the development of the child. One of the main goals is the long-term mothers to a lifestyle change to move that through healthy diets and increased physical activity will affect the whole fami

—

Countries

Germany

Contacts

Public ContactLydia Henneberger

Klinikum rechts der Isar der TU München Forschergruppe Diabetes der TU München

Lydia.Henneberger@lrz.uni-muenchen.de089-31874194

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026