Psychoneuroendocrine mechanisms of the regulation of hunger and satiety in obese and anorectic subjects

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00000442

Enrollment

Registered

2010-11-29

Start date

2010-09-08

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F50.0 F50.1 E66

Interventions

Group 1: Obese subjects (BMI > 30). Diagnostics of comobidities. Multimodal treatment with group psychotherapy, group music therapy, group art therapy, "Kommunikative Bewegungstherapie", behavior th

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. anorexic subjects (according ICD-10) (BMI 30) 3. normal weight control subjects (BMI 19-25) without relevant somatic disease 4. Healthy normal weight (BMI 19-25) women

Exclusion criteria

Exclusion criteria: 1. Carcinoma 2. Pregnancy during investigation

Design outcomes

Primary

Measure	Time frame
Complementary alterations in peptide hormone and enzyme levels (Oxytocin, CRF, Cortisol, CCK, Nesfatin, Ghrelin, Obestatin, PYY, Amylin, Leptin, NPY, CART, GOAT, DPP-IV, Insulin, TNF-alpha, Bombesin, GLP-1) during development towards weight restoration under treatment.	—

Secondary

Measure	Time frame
Significant correlations between subjective perceptions (hunger etc.) and psychological variables (anxiety, depression etc.) on the one and peptide hormone plasma levels on the other side (used psychometric instruments: EDI-2 FEV, PSQ, PHQ-9, ICD-10-symptom-rating, COPE, GAD-7, BSF, GBB). Moreover, significant correlations of peptide hormone plasma levels with measures of body composition, energy expenditure and physical activity.	—

Measure

Time frame

Significant correlations between subjective perceptions (hunger etc.) and psychological variables (anxiety, depression etc.) on the one and peptide hormone plasma levels on the other side (used psychometric instruments: EDI-2 FEV, PSQ, PHQ-9, ICD-10-symptom-rating, COPE, GAD-7, BSF, GBB). Moreover, significant correlations of peptide hormone plasma levels with measures of body composition, energy expenditure and physical activity.

—

Countries

Germany

Contacts

Public ContactTobias Hofmann

Medizinische Klinik m.S. PsychosomatikCharité - Universitätsmedizin BerlinCBF/CCM

tobias.hofmann@charite.de030-450553567

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026